Regeneration is one of the more common Essence types in the Infinite Reality. It's generated and released constantly by any entity with the Regeneration Conception, and stored within any Regeneration Essence Construct.

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Regeneration Essence is the almost massless physical manifestation of the concept of regeneration. It is released by constructs of the Regeneration Conception, Dao of Regeneration, ​any technique involving regenerating an Aspect, Resource, or even other kind of essence, or some other General Concept based on regeneration.​​​​

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When enough Regeneration Essence gathers in an area with another energy source, it can manifest a Regeneration Relic or Regeneration Heirloom. If an entity has a Grand Construct and at least one Regeneration Essence Construct, they can generate a generic Regeneration Antique, or a unique variety once they reach the Second Divine Tier.

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Despite being almost massless, Regeneration Essence can condense into physical Essence Stones, Liquid Essence, or a Manifested Essence Construct.

If an Essence Stone is refined or Looted from a slain foe, instead Quintessences are received.

Regeneration Essence Stones can manifest at Wunjo Essence Density. Liquid Regeneration Essence can manifest at Raido Essence Density. Manifested Regeneration Essence Constructs can manifest at Leldep or Vokuwrang Essence Density.​​